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TdT anticorps (N-Term) (FITC)

Cet anticorps Souris Monoclonal détecte spécifiquement TdT dans FACS. Il présente une réactivité envers Humain.
N° du produit ABIN294481

Aperçu rapide pour TdT anticorps (N-Term) (FITC) (ABIN294481)

Antigène

Voir toutes TdT (DNTT) Anticorps
TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Reactivité

  • 89
  • 29
  • 29
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
Humain

Hôte

  • 76
  • 15
Souris

Clonalité

  • 61
  • 29
  • 1
Monoclonal

Conjugué

  • 45
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Cet anticorp TdT est conjugé à/à la FITC

Application

  • 57
  • 37
  • 22
  • 8
  • 8
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Clone

HTdt-1-HTdt-2-HTdt-3
  • Épitope

    • 12
    • 8
    • 8
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Specificité

    Is a mixture of 3 monoclonal antibodies specific for human terminal deoxynucleotidyl transferase (TdT). TdT is a DNA polymerase responsible for the catalysis of non-reversible addition of deoxynucleotides to the 3 end hydroxy groups of DNA. TdT levels are enhanced in all forms of acute lymphoblastic leukaemia (ALL) and in a significant number of chronic lymphoblastic leukaemia cases (CML). TdT is not expressed in the majority of myeloid leukemias, non-Hodgkins lymphomas or mature lymphoid leukemias.

    Purification

    Purified

    Immunogène



    Type of Immunogen: Native protein
  • Indications d'application

    Approved: Flo (1:1)

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Membrane permeabilization is required for this application. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS, 0.09 % sodium azide, 1 % BSA.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Antigène

    TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

    Autre désignation

    DNTT / TdT

    Sujet

    Name/Gene ID: DNTT

    Synonyms: DNTT, DNA nucleotidylexotransferase, TDT, Terminal addition enzyme, Terminal transferase

    ID gène

    1791

    Pathways

    Réparation de l'ADN
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