Abeta 1-42 anticorps
Aperçu rapide pour Abeta 1-42 anticorps (ABIN2961828)
Antigène
Voir toutes Abeta 1-42 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Reacts with human and mouse Aβx-42
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Purification
- Purified
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Immunogène
- Synthetic peptide corresponding to Abeta35-42.
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Isotype
- IgG1
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Indications d'application
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
1 - 10 μg/mL -
Restrictions
- For Research Use only
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Buffer
- PBS pH 7.4
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Conseil sur la manipulation
- Dilute in PBS or medium which is identical to that used in the assay system.
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Stock
- -20 °C
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Stockage commentaire
- Stable for at least one year at -20°C
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Date de péremption
- 12 months
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- Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))
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Autre désignation
- Amyloid beta 1-42
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Sujet
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Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). The highly amyloidogenic 42-amino acid form of Aβ (Aβ42) and amino-terminally truncated forms of Aβ (Aβx-42) are the predominant species of Aβ typically found in diffuse and senile plaques within the AD brain. The relative levels of Aβ42 appear to be the key regulators of Aβ aggregation into amyloid, thus Aβ42 has been implicated as the initiating molecule in the pathogenesis of AD.
Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Beta-amyloid protein 42 Beta-APP42 Gene name: APP, A4, AD1 -
ID gène
- 351
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UniProt
- P05067
Antigène
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