BIRC7 anticorps

N° du produit ABIN298022

L’anticorps anti-BIRC7 Monoclonal Souris est utilisé pour la détection de BIRC7 dans des échantillons de Humain. Il a été validé pour WB, IHC et IHC (p).

Aperçu rapide pour BIRC7 anticorps (ABIN298022)

Antigène: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BIRC7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 88C570

Détail du produit anti-BIRC7 anticorps

Specificité: The Livin antibody, clone 88C570 has been shown to recognize both Livin alpha (~39 kD) and Livin beta (~37 kD) isoforms (Nachmias et al, 2003). 2. also recognizes the 30 kD (p30-Livin alpha) and 28 kD (p28-Livin beta) apoptotic cleavage fragments of Livin alpha and beta, respectively (Nachmias et al, 2003). Apoptotic cleavage fragments of Livin have also been referred to as truncated livin (tLivin) (Nachmias et al, 2007). 3. The specificity has been validated using Livin shRNA (Quiping et al, 2004).

Purification: Protein G purified

Immunogène: Recombinant human livin protein.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Information d'application

Indications d'application: Approved: IHC, IHC-P (10 μg/mL), WB (1 - 2 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS containing 0.05 % BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: avoid freeze thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Détails sur BIRC7

Antigène: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Autre désignation: BIRC7 / Livin

Sujet: Name/Gene ID: BIRC7
Family: Apoptosis

Synonyms: BIRC7, KIAP, Livin inhibitor of apoptosis, MLIAP, ML-IAP, RNF50, RING finger protein 50, LIVIN

ID gène: 79444

UniProt: Q96CA5