ITGAL anticorps (AA 26-306)
Aperçu rapide pour ITGAL anticorps (AA 26-306) (ABIN3015542)
Antigène
Voir toutes ITGAL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 26-306
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Séquence
- YNLDVRGARS FSPPRAGRHF GYRVLQVGNG VIVGAPGEGN STGSLYQCQS GTGHCLPVTL RGSNYTSKYL GMTLATDPTD GSILFAAVQF STSYKTEFDF SDYVKRKDPD ALLKHVKHML LLTNTFGAIN YVATEVFREE LGARPDATKV LIIITDGEAT DSGNIDAAKD IIRYIIGIGK HFQTKESQET LHKFASKPAS EFVKILDTFE KLKDLFTELQ KKIYVIEGTS KQDLTSFNME LSSSGISADL SRGHAVVGAV GAKDWAGGFL DLKADLQDDT F
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 26-306 of human CD11a/LFA-1A/ITGAL (NP_001107852.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- ITGAL (Integrin alpha-L (ITGAL))
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Autre désignation
- ITGAL
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Sujet
- ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.,CD11A,LFA-1,LFA1A,CD11a,ITGAL,Signal Transduction,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,T Cell Receptor Signaling Pathway,Stem Cells,Hematopoietic Progenitors,ITGAL
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Poids moléculaire
- 119 kDa/128 kDa/134 kDa
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ID gène
- 3683
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UniProt
- P20701
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Pathways
- Activated T Cell Proliferation, Integrin Complex
Antigène
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