ITGAL anticorps

N° du produit ABIN375486

Cité dans 1 publication. Cet anticorps anti-ITGAL Monoclonal Souris (Clone 38) (ABIN375486) détecte spécifiquement ITGAL dans FACS, IP, ELISA, IHC (fro), BR et Adh Act. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ITGAL anticorps (ABIN375486)

Antigène: ITGAL (Integrin alpha-L (ITGAL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGAL est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Adhesion Activation (Adh Act)

Clone: 38

Détail du produit anti-ITGAL anticorps

Fonction: Mouse Anti-Human CD11a-LE/AF

Attributs du produit: Low Endotoxin/Azide Free Anti-Human CD11a antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, ELISA, blocking, and adhesion assays.

niveau d'endotoxine: Low Endotoxin

Immunogène: Fibronectin purified monocytes

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Agent conservateur: Azide free

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: 2-8°C

Références pour anticorps anti-ITGAL (ABIN375486)

Venet, Ribeiro, Décembre, Bellomo, Joshi, Nuovo, Villard, Cluet, Perret, Pescamona, Paidassi, Walzer, Allatif, Belot, Trouillet-Assant, Ricci, Dreux: "Severe COVID-19 patients have impaired plasmacytoid dendritic cell-mediated control of SARS-CoV-2." dans: Nature communications, Vol. 14, Issue 1, pp. 694, (2023) (PubMed).

Détails sur ITGAL

Antigène: ITGAL (Integrin alpha-L (ITGAL))

Autre désignation: CD11a

Sujet: CD11a, also known as leukocyte function-associated antigen-1 (LFA-1 α ), represents the 180 kDa integrin α L subunit which combines with the CD18 β 2 integrin subunit to form the α L β 2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a/LFA-1 α mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.

ID gène: 3683

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex