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BRCA2 anticorps (AA 1-300)

BRCA2 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3016069
  • Antigène Voir toutes BRCA2 Anticorps
    BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
    Épitope
    • 15
    • 12
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-300
    Reactivité
    • 56
    • 23
    • 20
    • 4
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 55
    • 7
    Lapin
    Clonalité
    • 54
    • 8
    Polyclonal
    Conjugué
    • 31
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BRCA2 est non-conjugé
    Application
    • 37
    • 17
    • 13
    • 13
    • 9
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Séquence
    MPIGSKERPT FFEIFKTRCN KADLGPISLN WFEELSSEAP PYNSEPAEES EHKNNNYEPN LFKTPQRKPS YNQLASTPII FKEQGLTLPL YQSPVKELDK FKLDLGRNVP NSRHKSLRTV KTKMDQADDV SCPLLNSCLS ESPVVLQCTH VTPQRDKSVV CGSLFHTPKF VKGRQTPKHI SESLGAEVDP DMSWSSSLAT PPTLSSTVLI VRNEEASETV FPHDTTANVK SYFSNHDESL KKNDRFIASV TDSENTNQRE AASHGFGKTS GNSFKVNSCK DHIGKSMPNV LEDEVYETVV
     Réactivité croisée
    Humain, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human BRCA2 (NP_000050.2).
    Isotype
    IgG
    Top Product
    Discover our top product BRCA2 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
    Autre désignation
    BRCA2 (BRCA2 Produits)
    Synonymes
    anticorps BRCC2, anticorps BROVCA2, anticorps FACD, anticorps FAD, anticorps FAD1, anticorps FANCB, anticorps FANCD, anticorps FANCD1, anticorps GLM3, anticorps PNCA2, anticorps 30169, anticorps BcDNA:SD25109, anticorps CG13583, anticorps CG13584, anticorps CG30169, anticorps Dmel\\CG30169, anticorps brca2, anticorps dmbrca2, anticorps fancd1, anticorps BRCA2, anticorps brcc2, anticorps brovca2, anticorps facd, anticorps fad, anticorps fad1, anticorps fancb, anticorps AI256696, anticorps AW045498, anticorps Fancd1, anticorps RAB163, anticorps BRCA2, DNA repair associated, anticorps Breast cancer 2, early onset homolog, anticorps breast cancer 2, early onset, anticorps BRCA2, anticorps Brca2, anticorps brca2, anticorps LOC584780
    Sujet
    Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.,BRCA2,BRCC2,BROVCA2,FACD,FAD,FAD1,FANCD,FANCD1,GLM3,PNCA2,XRCC11,Epigenetics & Nuclear Signaling,Transcription Factors,DNA Damage & Repair,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,BRCA2
    Poids moléculaire
    384 kDa
    ID gène
    675
    UniProt
    P51587
    Pathways
    Réparation de l'ADN, M Phase, Maintenance of Protein Location
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