PRG2 anticorps (AA 17-222)
Aperçu rapide pour PRG2 anticorps (AA 17-222) (ABIN3016204)
Antigène
Voir toutes PRG2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 17-222
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Séquence
- LHLRSETSTF ETPLGAKTLP EDEETPEQEM EETPCRELEE EEEWGSGSED ASKKDGAVES ISVPDMVDKN LTCPEEEDTV KVVGIPGCQT CRYLLVRSLQ TFSQAWFTCR RCYRGNLVSI HNFNINYRIQ CSVSALNQGQ VWIGGRITGS GRCRRFQWVD GSRWNFAYWA AHQPWSRGGH CVALCTRGGH WRRAHCLRRL PFICSY
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 17-222 of human PRG2 (NP_002719.3).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- PRG2 (Bone Marrow Proteoglycan (PRG2))
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Autre désignation
- PRG2
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Sujet
- The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PRG2,BMPG,MBP,MBP1,proMBP,PRG2
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Poids moléculaire
- 23 kDa/25 kDa
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ID gène
- 5553
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UniProt
- P13727
Antigène
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