ADRA2A anticorps (AA 240-380)

N° du produit ABIN3016752

Cet anticorps Lapin Polyclonal détecte spécifiquement ADRA2A dans WB et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour ADRA2A anticorps (AA 240-380) (ABIN3016752)

Antigène: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRA2A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-ADRA2A anticorps

Épitope: AA 240-380

Séquence: RRTRVPPSRR GPDAVAAPPG GTERRPNGLG PERSAGPGGA EAEPLPTQLN GAPGEPAPAG PRDTDALDLE ESSSSDHAER PPGPRRPERG PRGKGKARAS QVKPGDSLPR RGPGATGIGT PAAGPGEERV GAAKASRWRG R

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human ADRA2A (NP_000672.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ADRA2A

Antigène: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Autre désignation: ADRA2A

Sujet: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons, the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences.,ADRA2A,ADRA2,ADRA2R,ADRAR,ALPHA2AAR,ZNF32,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,AMPK Signaling Pathway,Neuroscience,ADRA2A

Poids moléculaire: 48 kDa

ID gène: 150

UniProt: P08913

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity