ATG4B anticorps (AA 1-393)

N° du produit ABIN3016809

Il existe 4+ publications pour ce produit. L’anticorps anti-ATG4B Polyclonal Lapin est utilisé pour la détection de ATG4B dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour ATG4B anticorps (AA 1-393) (ABIN3016809)

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG4B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ATG4B anticorps

Épitope: AA 1-393

Séquence: MDAATLTYDT LRFAEFEDFP ETSEPVWILG RKYSIFTEKD EILSDVASRL WFTYRKNFPA IGGTGPTSDT GWGCMLRCGQ MIFAQALVCR HLGRDWRWTQ RKRQPDSYFS VLNAFIDRKD SYYSIHQIAQ MGVGEGKSIG QWYGPNTVAQ VLKKLAVFDT WSSLAVHIAM DNTVVMEEIR RLCRTSVPCA GATAFPADSD RHCNGFPAGA EVTNRPSPWR PLVLLIPLRL GLTDINEAYV ETLKHCFMMP QSLGVIGGKP NSAHYFIGYV GEELIYLDPH TTQPAVEPTD GCFIPDESFH CQHPPCRMSI AELDPSIAVG FFCKTEDDFN DWCQQVKKLS LLGGALPMFE LVELQPSHLA CPDVLNLSLD SSDVERLERF FDSEDEDFEI LSL

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-393 of human ATG4B (NP_037457.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-ATG4B (ABIN3016809)

Li, Zhao, Wang, Shao, Wang, Wang, Xing: "Regulation of autophagy factors by oxidative stress and cardiac enzymes imbalance during arsenic or/and copper induced cardiotoxicity in Gallus gallus." dans: Ecotoxicology and environmental safety, Vol. 148, pp. 125-134, (2018) (PubMed).

Sun, Li, Zhao, Wang, Liu, Shao, Xue, Xing: "Synergistic effect of copper and arsenic upon oxidative stress, inflammation and autophagy alterations in brain tissues of Gallus gallus." dans: Journal of inorganic biochemistry, Vol. 178, pp. 54-62, (2018) (PubMed).

Shao, Zhao, Wang, Liu, Zong, Xing: "Copper-Mediated Mitochondrial Fission/Fusion Is Associated with Intrinsic Apoptosis and Autophagy in the Testis Tissues of Chicken." dans: Biological trace element research, (2018) (PubMed).

Shao, Zhao, Wang, Liu, Li, Luo, Xing: "The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken." dans: Poultry science, Vol. 97, Issue 9, pp. 3248-3257, (2018) (PubMed).

Détails sur ATG4B

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Autre désignation: ATG4B

Sujet: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,ATG4B,APG4B,AUTL1,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Extracellular Matrix,Ubiquitin,Endocrine & Metabolism,Mitochondrial metabolism,Cardiovascular,Heart,ATGs,ATG4B

Poids moléculaire: 31 kDa/37 kDa/42 kDa/44 kDa/52 kDa

ID gène: 23192

UniProt: Q9Y4P1

Pathways: Autophagy