CCR2 anticorps (AA 315-374)

N° du produit ABIN3016845

Cet anticorps Lapin Polyclonal détecte spécifiquement CCR2 dans WB. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour CCR2 anticorps (AA 315-374) (ABIN3016845)

Antigène: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CCR2 anticorps

Épitope: AA 315-374

Séquence: LFHIALGCRI APLQKPVCGG PGVRPGKNVK VTTQGLLDGR GKGKSIGRAP EASLQDKEGA

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 315-374 of human CCR2 (NP_001116513.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-CCR2 (ABIN3016845)

Deci, Ferguson, Scatigno, Nguyen: "Modulating Macrophage Polarization through CCR2 Inhibition and Multivalent Engagement." dans: Molecular pharmaceutics, Vol. 15, Issue 7, pp. 2721-2731, (2018) (PubMed).

Détails sur CCR2

Antigène: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Autre désignation: CCR2

Sujet: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.,CCR2,CC-CKR-2,CCR-2,CCR2A,CCR2B,CD192,CKR2,CKR2A,CKR2B,CMKBR2,MCP-1-R,FLJ78302,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,Chemokines,Chemokine,Cardiovascular,CCR2

Poids moléculaire: 41 kDa

ID gène: 729230

UniProt: P41597

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process