CHRNA10 anticorps (AA 25-240)

N° du produit ABIN3017240

Détail du produit anti-CHRNA10 anticorps

Antigène: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Épitope: AA 25-240

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNA10 est non-conjugé

Application: Western Blotting (WB)

Séquence: AEGRLALKLF RDLFANYTSA LRPVADTDQT LNVTLEVTLS QIIDMDERNQ VLTLYLWIRQ EWTDAYLRWD PNAYGGLDAI RIPSSLVWRP DIVLYNKADA QPPGSASTNV VLRHDGAVRW DAPAITRSSC RVDVAAFPFD AQHCGLTFGS WTHGGHQLDV RPRGAAASLA DFVENVEWRV LGMPARRRVL TYGCCSEPYP DVTFTLLLRR RAAAYV

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 25-240 of human CHRNA10 (NP_065135.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CHRNA10

Antigène: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Autre désignation: CHRNA10 (CHRNA10 Produits)

Synonymes: anticorps si:dkey-24p1.3, anticorps ALPHA 10 nAChR, anticorps cholinergic receptor, nicotinic, alpha polypeptide 10, anticorps cholinergic receptor nicotinic alpha 10 subunit, anticorps cholinergic receptor, nicotinic, alpha 10a, anticorps neuronal acetylcholine receptor subunit alpha-10, anticorps cholinergic receptor, nicotinic, alpha 10 (neuronal), anticorps Chrna10, anticorps CHRNA10, anticorps chrna10a, anticorps LOC100344381

Sujet: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.,CHRNA10,Signal Transduction,Neuroscience,Calcium Signaling,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRNA10

Poids moléculaire: 49 kDa

ID gène: 57053

UniProt: Q9GZZ6

Pathways: Sensory Perception of Sound, Synaptic Membrane