CHRNA10 anticorps (C-Term)

N° du produit ABIN6258708

Détail du produit anti-CHRNA10 anticorps

Antigène: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNA10 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: CHRNA10 Antibody detects endogenous levels of total CHRNA10.

Homologie: Pig,Bovine,Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CHRNA10, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CHRNA10

Antigène: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Autre désignation: CHRNA10 (CHRNA10 Produits)

Synonymes: anticorps si:dkey-24p1.3, anticorps ALPHA 10 nAChR, anticorps cholinergic receptor, nicotinic, alpha polypeptide 10, anticorps cholinergic receptor nicotinic alpha 10 subunit, anticorps cholinergic receptor, nicotinic, alpha 10a, anticorps neuronal acetylcholine receptor subunit alpha-10, anticorps cholinergic receptor, nicotinic, alpha 10 (neuronal), anticorps Chrna10, anticorps CHRNA10, anticorps chrna10a, anticorps LOC100344381

Sujet:

Description: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Gene: CHRNA10

Poids moléculaire: 50 kDa

ID gène: 57053

UniProt: Q9GZZ6

Pathways: Sensory Perception of Sound, Synaptic Membrane