NFASC anticorps (AA 830-1100)

N° du produit ABIN3017267

Cet anticorps Lapin Polyclonal détecte spécifiquement NFASC dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour NFASC anticorps (AA 830-1100) (ABIN3017267)

Antigène: NFASC (Neurofascin (NFASC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFASC est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NFASC anticorps

Épitope: AA 830-1100

Séquence: RFRVRQPNLE TINLEWDHPE HPNGIMIGYT LKYVAFNGTK VGKQIVENFS PNQTKFTVQR TDPVSRYRFT LSARTQVGSG EAVTEESPAP PNEATPTAAP PTLPPTTVGA TGAVSSTDAT AIAATTEATT VPIIPTVAPT TIATTTTVAT TTTTTAAATT TTESPPTTTS GTKIHESAPD EQSIWNVTVL PNSKWANITW KHNFGPGTDF VVEYIDSNHT KKTVPVKAQA QPIQLTDLYP GMTYTLRVYS RDNEGISSTV ITFMTSTAYT N

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 830-1100 of human NFASC (NP_001005388.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NFASC

Antigène: NFASC (Neurofascin (NFASC))

Autre désignation: NFASC

Sujet: This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.,NFASC,NF,NRCAML,Neuroscience,NFASC

Poids moléculaire: 69 kDa/119 kDa/130-150 kDa

ID gène: 23114

UniProt: O94856

Pathways: Cell-Cell Junction Organization