CARD8 anticorps (AA 1-200)

N° du produit ABIN3020898

Cet anticorps anti-CARD8 est un anticorps Lapin Polyclonal détectant CARD8 dans WB. Adapté pour Humain.

Aperçu rapide pour CARD8 anticorps (AA 1-200) (ABIN3020898)

Antigène: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARD8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CARD8 anticorps

Épitope: AA 1-200

Séquence: MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLLLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG DRLTGIPSHI LNSSPSDRQI NQLAQRLGPE WEPMVLSLGL SQTDIYRCKA NHPHNVQSQV VEAFIRWRQR FGKQATFQSL HNGLRAVEVD PSLLLHMLE

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CARD8 (NP_003796.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CARD8

Antigène: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Autre désignation: CARD8

Sujet: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.,CARD8,CARDINAL,DACAR,DAKAR,NDPP,NDPP1,TUCAN,Cell Biology & Developmental Biology,Apoptosis,Caspases,CARD8

Poids moléculaire: 32 kDa/44 kDa/48 kDa/55 kDa/60 kDa

ID gène: 22900

UniProt: Q9Y2G2

Pathways: Positive Regulation of Endopeptidase Activity