S100B anticorps (AA 1-92)

N° du produit ABIN3021048

Il existe 2+ publications pour ce produit. L’anticorps anti-S100B Polyclonal Lapin est utilisé pour la détection de S100B dans des échantillons de Humain. Il a été validé pour WB, IHC, IF et IP.

Aperçu rapide pour S100B anticorps (AA 1-92) (ABIN3021048)

Antigène: S100B (S100 Calcium Binding Protein B (S100B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp S100B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-S100B anticorps

Épitope: AA 1-92

Séquence: MSELEKAMVA LIDVFHQYSG REGDKHKLKK SELKELINNE LSHFLEEIKE QEVVDKVMET LDNDGDGECD FQEFMAFVAM VTTACHEFFE HE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100B (NP_006263.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-S100B (ABIN3021048)

Yao, Zhao, Tang, Xiong, Zhao, Liu, Dong, Zou, Cai: "Blockade of β-catenin signaling attenuates toluene diisocyanate-induced experimental asthma." dans: Allergy, Vol. 72, Issue 4, pp. 579-589, (2017) (PubMed).

Yao, Zhao, Tang, Liang, Liu, Dong, Zou, Cai: "The receptor for advanced glycation end products is required for β-catenin stabilization in a chemical-induced asthma model." dans: British journal of pharmacology, Vol. 173, Issue 17, pp. 2600-13, (2017) (PubMed).

Détails sur S100B

Antigène: S100B (S100 Calcium Binding Protein B (S100B))

Autre désignation: S100B

Sujet: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.,NEF,S100,S100-B,S100beta,S100B,S100 beta,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell differentiation,Neuroscience,Cell Type Marker,Stem Cells,Neural Stem Cells,S100B

Poids moléculaire: 10 kDa

ID gène: 6285

UniProt: P04271

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins