MMP7 anticorps (AA 18-267)

N° du produit ABIN3021103

L’anticorps Lapin Polyclonal anti-MMP7 a été validé pour WB, IHC et IF. Il convient pour détecter MMP7 dans des échantillons de Humain.

Aperçu rapide pour MMP7 anticorps (AA 18-267) (ABIN3021103)

Antigène: MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MMP7 anticorps

Épitope: AA 18-267

Séquence: LPLPQEAGGM SELQWEQAQD YLKRFYLYDS ETKNANSLEA KLKEMQKFFG LPITGMLNSR VIEIMQKPRC GVPDVAEYSL FPNSPKWTSK VVTYRIVSYT RDLPHITVDR LVSKALNMWG KEIPLHFRKV VWGTADIMIG FARGAHGDSY PFDGPGNTLA HAFAPGTGLG GDAHFDEDER WTDGSSLGIN FLYAATHELG HSLGMGHSSD PNAVMYPTYG NGDPQNFKLS QDDIKGIQKL YGKRSNSRKK

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 18-267 of human MMP7 (NP_002414.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MMP7

Antigène: MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Autre désignation: MMP7

Sujet: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers.,MMP7,MMP-7,MPSL1,PUMP-1,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,Cardiovascular,Angiogenesis,MMP7

Poids moléculaire: 29 kDa

ID gène: 4316

UniProt: P09237

Pathways: Production of Molecular Mediator of Immune Response