Cet anticorps Lapin Polyclonal détecte spécifiquement Hexokinase 2 dans WB, IHC et IF. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid freeze / thaw cycles
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Guo, Yao, Zhan, Hu, Yue, Cheng, Liu, Ye, Qing, Zhang, Liu: "N-methylhemeanthidine chloride, a novel Amaryllidaceae alkaloid, inhibits pancreatic cancer cell proliferation via down-regulating AKT activation." dans: Toxicology and applied pharmacology, Vol. 280, Issue 3, pp. 475-83, (2014) (PubMed).
Antigène
Hexokinase 2 (HK2)
Autre désignation
HK2
Sujet
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.,HK2,HKII,HXK2,hexokinase-2,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Warburg Effect,Cardiovascular,Heart,Cardiac metabolism,HK2