Hexokinase 2 anticorps (AA 1-120)

N° du produit ABIN3021256

Détail du produit anti-Hexokinase 2 anticorps

Antigène: Hexokinase 2 (HK2)

Épitope: AA 1-120

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hexokinase 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MIASHLLAYF FTELNHDQVQ KVDQYLYHMR LSDETLLEIS KRFRKEMEKG LGATTHPTAA VKMLPTFVRS TPDGTEHGEF LALDLGGTNF RVLWVKVTDN GLQKVEMENQ IYAIPEDIMR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Hexokinase II (NP_000180.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Hexokinase 2 (ABIN3021256)

Guo, Yao, Zhan, Hu, Yue, Cheng, Liu, Ye, Qing, Zhang, Liu: "N-methylhemeanthidine chloride, a novel Amaryllidaceae alkaloid, inhibits pancreatic cancer cell proliferation via down-regulating AKT activation." dans: Toxicology and applied pharmacology, Vol. 280, Issue 3, pp. 475-83, (2014) (PubMed).

Détails sur Hexokinase 2

Antigène: Hexokinase 2 (HK2)

Autre désignation: HK2 (HK2 Produits)

Synonymes: anticorps HKII, anticorps HXK2, anticorps AI642394, anticorps hexokinase-2, anticorps fi09d05, anticorps fi17h06, anticorps wu:fi09d05, anticorps wu:fi17h06, anticorps wu:fi31b04, anticorps zgc:55926, anticorps HK2, anticorps ARABIDOPSIS THALIANA HEXOKINASE 2, anticorps ATHXK2, anticorps F6F22.11, anticorps F6F22_11, anticorps HEXOKINASE 2, anticorps hexokinase 2, anticorps StHK2, anticorps hexokinase 2, anticorps hexokinase-2, anticorps hexokinase 2 L homeolog, anticorps HK2, anticorps Hk2, anticorps hk2, anticorps HXK2, anticorps LOC100032849, anticorps hk2.L, anticorps hxk2, anticorps LOC102577690

Sujet: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.,HK2,HKII,HXK2,hexokinase-2,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Warburg Effect,Cardiovascular,Heart,Cardiac metabolism,HK2

Poids moléculaire: 102 kDa

ID gène: 3099

UniProt: P52789

Pathways: Signalisation PI3K-Akt, Carbohydrate Homeostasis, L'effet Warburg