MCM7 anticorps (AA 360-719)

N° du produit ABIN3021521

Cet anticorps Lapin Polyclonal détecte spécifiquement MCM7 dans WB, IF et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour MCM7 anticorps (AA 360-719) (ABIN3021521)

Antigène: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-MCM7 anticorps

Épitope: AA 360-719

Séquence: GGVDQSPRGM KIRGNINICL MGDPGVAKSQ LLSYIDRLAP RSQYTTGRGS SGVGLTAAVL RDSVSGELTL EGGALVLADQ GVCCIDEFDK MAEADRTAIH EVMEQQTISI AKAGILTTLN ARCSILAAAN PAYGRYNPRR SLEQNIQLPA ALLSRFDLLW LIQDRPDRDN DLRLAQHITY VHQHSRQPPS QFEPLDMKLM RRYIAMCREK QPMVPESLAD YITAAYVEMR REAWASKDAT YTSARTLLAI LRLSTALARL RMVDVVEKED VNEAIRLMEM SKDSLLGDKG QTARTQRPAD VIFATVRELV SGGRSVRFSE AEQRCVSRGF TPAQFQAALD EYEELNVWQV NASRTRITFV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 360-719 of human MCM7 (NP_005907.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MCM7

Antigène: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Autre désignation: MCM7

Sujet: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.,MCM7,CDC47,MCM2,P1.1-MCM3,P1CDC47,P85MCM,PNAS146,PPP1R104,Epigenetics & Nuclear Signaling,MCM7

Poids moléculaire: 44 kDa/60 kDa/81 kDa

ID gène: 4176

UniProt: P33993

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA