TCF4 anticorps (AA 400-500)

N° du produit ABIN3021530

Cet anticorps Lapin Polyclonal détecte spécifiquement TCF4 dans WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour TCF4 anticorps (AA 400-500) (ABIN3021530)

Antigène: TCF4 (Transcription Factor 4 (TCF4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCF4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-TCF4 anticorps

Épitope: AA 400-500

Séquence: LRNHAVGPST AMPGGHGDMH GIIGPSHNGA MGGLGSGYGT GLLSANRHSL MVGTHREDGV ALRGSHSLLP NQVPVPQLPV QSATSPDLNP PQDPYRGMPP G

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 400-500 of human TCF4 (NP_001077431.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TCF4

Antigène: TCF4 (Transcription Factor 4 (TCF4))

Autre désignation: TCF4

Sujet: This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.,TCF4,E2-2,FECD3,ITF-2,ITF2,PTHS,SEF-2,SEF2,SEF2-1,SEF2-1A,SEF2-1B,SEF2-1D,TCF-4,bHLHb19,TCF4,Epigenetics & Nuclear Signaling,Transcription Factors,Stem Cells,TCF4

Poids moléculaire: 48-71 kDa

ID gène: 6925

UniProt: P15884

Pathways: Signalisation WNT, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus