ARHGDIA anticorps (AA 1-204)
Aperçu rapide pour ARHGDIA anticorps (AA 1-204) (ABIN3021744)
Antigène
Voir toutes ARHGDIA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-204
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Séquence
- MAEQEPTAEQ LAQIAAENEE DEHSVNYKPP AQKSIQEIQE LDKDDESLRK YKEALLGRVA VSADPNVPNV VVTGLTLVCS SAPGPLELDL TGDLESFKKQ SFVLKEGVEY RIKISFRVNR EIVSGMKYIQ HTYRKGVKID KTDYMVGSYG PRAEEYEFLT PVEEAPKGML ARGSYSIKSR FTDDDKTDHL SWEWNLTIKK DWKD
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-204 of human RhoGDI (NP_001172006.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))
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Autre désignation
- ARHGDIA
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Sujet
- This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.,ARHGDIA,GDIA1,HEL-S-47e,NPHS8,RHOGDI,RHOGDI-1,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,ARHGDIA
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Poids moléculaire
- 18 kDa/23 kDa
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ID gène
- 396
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UniProt
- P52565
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Pathways
- Neurotrophin Signaling Pathway
Antigène
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