Syndecan 1 anticorps (AA 25-240)
Aperçu rapide pour Syndecan 1 anticorps (AA 25-240) (ABIN3021805)
Antigène
Voir toutes Syndecan 1 (SDC1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 25-240
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Séquence
- VATNLPPEDQ DGSGDDSDNF SGSGAGALQD ITLSQQTPST WKDTQLLTAI PTSPEPTGLE ATAASTSTLP AGEGPKEGEA VVLPEVEPGL TAREQEATPR PRETTQLPTT HQASTTTATT AQEPATSHPH RDMQPGHHET STPAGPSQAD LHTPHTEDGG PSATERAAED GASSQLPAAE GSGEQDFTFE TSGENTAVVA VEPDRRNQSP VDQGAT
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 25-240 of human CD138/Syndecan-1 (NP_002988.3).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Syndecan 1 (SDC1)
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Autre désignation
- SDC1
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Sujet
- The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.,SDC1,CD138,SDC,SYND1,syndecan,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,CD markers,Neuroscience,Cell Type Marker,Stem Cells,Hematopoietic Progenitors,Neuron marker,Synapse marker,SDC1
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Poids moléculaire
- 32 kDa
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ID gène
- 6382
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UniProt
- P18827
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Pathways
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
Antigène
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