MITF anticorps (AA 1-280)

N° du produit ABIN3021855

Cité dans 2 publications. Cet anticorps anti-MITF Polyclonal Lapin (ABIN3021855) détecte spécifiquement MITF dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MITF anticorps (AA 1-280) (ABIN3021855)

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MITF est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MITF anticorps

Épitope: AA 1-280

Séquence: MLEMLEYNHY QVQTHLENPT KYHIQQAQRQ QVKQYLSTTL ANKHANQVLS LPCPNQPGDH VMPPVPGSSA PNSPMAMLTL NSNCEKEGFY KFEEQNRAES ECPGMNTHSR ASCMQMDDVI DDIISLESSY NEEILGLMDP ALQMANTLPV SGNLIDLYGN QGLPPPGLTI SNSCPANLPN IKRELTESEA RALAKERQKK DNHNLIERRR RFNINDRIKE LGTLIPKSND PDMRWNKGTI LKASVDYIRK LQREQQRAKE LENRQKKLEH ANRHLLLRIQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human MITF (NP_937801.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-MITF (ABIN3021855)

Zhang, Yue, Jiang, Wang, Liu: "Identification of an MITF gene and its polymorphisms associated with the Vibrio resistance trait in the clam Meretrix petechialis." dans: Fish & shellfish immunology, Vol. 68, pp. 466-473, (2018) (PubMed).

Zhang, Wang, Yu, Jiang, Yue, Liu: "Identification of a gene encoding microphthalmia-associated transcription factor and its association with shell color in the clam Meretrix petechialis." dans: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, Vol. 225, pp. 75-83, (2018) (PubMed).

Détails sur MITF

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Autre désignation: MITF

Sujet: This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.,MITF,CMM8,COMMAD,MI,WS2,WS2A,bHLHe32,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-Erk Signaling Pathway,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,MITF

Poids moléculaire: 40 kDa/46 kDa/52 kDa/55 kDa/56 kDa/57 kDa/58 kDa

ID gène: 4286

UniProt: O75030

Pathways: Chromatin Binding