MITF anticorps (AA 351-450)

N° du produit ABIN676373

Détail du produit anti-MITF anticorps

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Épitope: AA 351-450

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MITF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MITF

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-MITF (ABIN676373)

Rice, Cebra-Thomas, Haugas, Partanen, Rice, Gilbert: "Melanoblast development coincides with the late emerging cells from the dorsal neural tube in turtle Trachemys scripta." dans: Scientific reports, Vol. 7, Issue 1, pp. 12063, (2019) (PubMed).

Kito, Saigo, Takeuchi: "Novel Transgenic Mouse Model of Polycystic Kidney Disease." dans: The American journal of pathology, Vol. 187, Issue 9, pp. 1916-1922, (2017) (PubMed).

Han, Sung, Lee: "Antimelanogenesis Activity of Hydrolyzed Ginseng Extract (GINST) via Inhibition of JNK Mitogen-activated Protein Kinase in B16F10 Cells." dans: Journal of food science, Vol. 81, Issue 8, pp. H2085-92, (2016) (PubMed).

Détails sur MITF

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Autre désignation: Mitf (MITF Produits)

Synonymes: anticorps MITF, anticorps ws2a, anticorps mitfa, anticorps MITF-A, anticorps LOC100313655, anticorps mitfb, anticorps CMM8, anticorps MI, anticorps WS2, anticorps WS2A, anticorps bHLHe32, anticorps BCC2, anticorps Bhlhe32, anticorps Gsfbcc2, anticorps Vitiligo, anticorps Wh, anticorps bw, anticorps mi, anticorps vit, anticorps MITF-H, anticorps MITF-M, anticorps CMI9, anticorps melanogenesis associated transcription factor, anticorps microphthalmia-associated transcription factor, anticorps microphthalmia-associated transcription factor S homeolog, anticorps Microphthalmia, anticorps MITF, anticorps mitf, anticorps LOC100313655, anticorps mitf.S, anticorps LOC100534525, anticorps MICROP, anticorps Mitf

Sujet:

Synonyms: MI, WS2, CMM8, WS2A, bHLHe32, Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, MITF

Background: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

ID gène: 4286

UniProt: O75030

Pathways: Chromatin Binding