HMOX1 anticorps (AA 1-288)

N° du produit ABIN3021907

Cet anticorps Lapin Polyclonal détecte spécifiquement HMOX1 dans WB, IHC et IF. Il présente une réactivité envers Humain et a été mentionné dans 9+ publications.

Aperçu rapide pour HMOX1 anticorps (AA 1-288) (ABIN3021907)

Antigène: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMOX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-HMOX1 anticorps

Épitope: AA 1-288

Séquence: MERPQPDSMP QDLSEALKEA TKEVHTQAEN AEFMRNFQKG QVTRDGFKLV MASLYHIYVA LEEEIERNKE SPVFAPVYFP EELHRKAALE QDLAFWYGPR WQEVIPYTPA MQRYVKRLHE VGRTEPELLV AHAYTRYLGD LSGGQVLKKI AQKALDLPSS GEGLAFFTFP NIASATKFKQ LYRSRMNSLE MTPAVRQRVI EEAKTAFLLN IQLFEELQEL LTHDTKDQSP SRAPGLRQRA SNKVQDSAPV ETPRGKPPLN TRSQAPLLRW VLTLSFLVAT VAVGLYAM

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-288 of human Heme Oxygenase 1 (HO-1/HMOX1) (NP_002124.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-HMOX1 (ABIN3021907)

Xie, Chen, Tao: "Astaxanthin Promotes Nrf2/ARE Signaling to Inhibit HG-Induced Renal Fibrosis in GMCs." dans: Marine drugs, Vol. 16, Issue 4, (2018) (PubMed).

Wang, Zheng, Zhang, Zhao, Wang, Wang, Shang, Barasch, Qiu: "Physiological functions of ferroportin in the regulation of renal iron recycling and ischemic acute kidney injury." dans: American journal of physiology. Renal physiology, Vol. 315, Issue 4, pp. F1042-F1057, (2018) (PubMed).

Khaliq, Jing, Ke, Ke-Li, Peng-Peng, Cui, Wei-Wei, Zhixin, Hua-Zhen, Hui, Ju-Ming, Ke-Mei: "Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks." dans: Biological trace element research, Vol. 186, Issue 1, pp. 226-237, (2018) (PubMed).

Qiu, Wu, Meng, Luo, Zhao, Sun, Gao: "GYY4137 protects against myocardial ischemia/reperfusion injury via activation of the PHLPP-1/Akt/Nrf2 signaling pathway in diabetic mice." dans: The Journal of surgical research, Vol. 225, pp. 29-39, (2018) (PubMed).

Zhang, Chen, Gong, Zou, Xu, Chen, Huang: "Paeonol Ameliorates Diabetic Renal Fibrosis Through Promoting the Activation of the Nrf2/ARE Pathway via Up-Regulating Sirt1." dans: Frontiers in pharmacology, Vol. 9, pp. 512, (2018) (PubMed).

Chen, Xie, Huang, Gong, Zhu, Chen, Huang, Huang: "Connexin43 regulates high glucose-induced expression of fibronectin, ICAM-1 and TGF-β1 via Nrf2/ARE pathway in glomerular mesangial cells." dans: Free radical biology & medicine, Vol. 102, pp. 77-86, (2016) (PubMed).

Chen, Lai, Yang, Ruan, Chaugai, Ning, Chen, Wang: "Trimetazidine prevents macrophage-mediated septic myocardial dysfunction via activation of the histone deacetylase sirtuin 1." dans: British journal of pharmacology, Vol. 173, Issue 3, pp. 545-61, (2016) (PubMed).

Gao, Yang, Shi, Xu, Li, Xia, Wu, Yao, Wang, Yuan: "Diabetes blocks the cardioprotective effects of sevoflurane postconditioning by impairing Nrf2/Brg1/HO-1 signaling." dans: European journal of pharmacology, Vol. 779, pp. 111-21, (2016) (PubMed).

Geng, Zhang, Gao, Tao, Zhang, Liu, Fang, Chang: "Mst1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice." dans: Biochemical and biophysical research communications, Vol. 471, Issue 4, pp. 444-9, (2016) (PubMed).

Détails sur HMOX1

Antigène: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Autre désignation: HMOX1

Sujet: Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.,HMOX1,HMOX1D,HO-1,HSP32,bK286B10,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,Blood,Hypoxia,HMOX1

Poids moléculaire: 32 kDa

ID gène: 3162

UniProt: P09601

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome