Osteopontin anticorps (AA 17-314)
Aperçu rapide pour Osteopontin anticorps (AA 17-314) (ABIN3021922)
Antigène
Voir toutes Osteopontin (SPP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 17-314
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Séquence
- IPVKQADSGS SEEKQLYNKY PDAVATWLNP DPSQKQNLLA PQNAVSSEET NDFKQETLPS KSNESHDHMD DMDDEDDDDH VDSQDSIDSN DSDDVDDTDD SHQSDESHHS DESDELVTDF PTDLPATEVF TPVVPTVDTY DGRGDSVVYG LRSKSKKFRR PDIQYPDATD EDITSHMESE ELNGAYKAIP VAQDLNAPSD WDSRGKDSYE TSQLDDQSAE THSHKQSRLY KRKANDESNE HSDVIDSQEL SKVSREFHSH EFHSHEDMLV VDPKSKEEDK HLKFRISHEL DSASSEVN
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 17-314 of human Osteopontin (NP_001035147.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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: "MicroRNA-195-5p Regulates Osteogenic Differentiation of Periodontal Ligament Cells Under Mechanical Loading." dans: Journal of cellular physiology, Vol. 232, Issue 12, pp. 3762-3774, (2017) (PubMed).
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- Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))
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Autre désignation
- SPP1
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Sujet
- The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.,BNSP,BSPI,ETA-1,OPN,Osteopontin,SPP1,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Extracellular Matrix,Bone,Growth factor,Immunology & Inflammation,Cytokines,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Angiogenesis,SPP1
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Poids moléculaire
- 32 kDa/33 kDa/35 kDa
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ID gène
- 6696
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UniProt
- P10451
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Pathways
- Regulation of Cell Size
Antigène
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