ENOS anticorps (AA 1-120)

N° du produit ABIN3022122

Cet anticorps Lapin Polyclonal détecte spécifiquement ENOS dans WB et IF. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour ENOS anticorps (AA 1-120) (ABIN3022122)

Antigène: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ENOS est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-ENOS anticorps

Épitope: AA 1-120

Séquence: MGNLKSVAQE PGPPCGLGLG LGLGLCGKQG PATPAPEPSR APASLLPPAP EHSPPSSPLT QPPEGPKFPR VKNWEVGSIT YDTLSAQAQQ DGPCTPRRCL GSLVFPRKLQ GRPSPGPPAP

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human eNOS (NP_000594.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-ENOS (ABIN3022122)

Luo, Dan Wang, Luo, Zhu, Wang, Ning, Li, Ma, Yang, Jin, Huang, Meng, Li: "Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration." dans: Redox biology, Vol. 13, pp. 508-521, (2018) (PubMed).

Luo, Wang, Zhu, Wang, You, Ning, Li, Jin, Huang, Hu, Chen, Meng, Li: "Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration." dans: Cell death & disease, Vol. 9, Issue 5, pp. 576, (2018) (PubMed).

Détails sur ENOS

Antigène: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Autre désignation: NOS3

Sujet: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants.,NOS3,ECNOS,eNOS,Cancer,Signal Transduction,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Endocrine & Metabolism,AMPK Signaling Pathway,Neuroscience,Cardiovascular,Angiogenesis,Blood,Hypoxia,NOS3

Poids moléculaire: 67 kDa/68 kDa/133 kDa

ID gène: 4846

UniProt: P29474

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling