KEAP1 anticorps (AA 325-624)

N° du produit ABIN3022609

L’anticorps Lapin Polyclonal anti-KEAP1 a été validé pour WB, IHC et IF. Il convient pour détecter KEAP1 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour KEAP1 anticorps (AA 325-624) (ABIN3022609)

Antigène: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KEAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-KEAP1 anticorps

Épitope: AA 325-624

Séquence: GRLIYTAGGY FRQSLSYLEA YNPSDGTWLR LADLQVPRSG LAGCVVGGLL YAVGGRNNSP DGNTDSSALD CYNPMTNQWS PCAPMSVPRN RIGVGVIDGH IYAVGGSHGC IHHNSVERYE PERDEWHLVA PMLTRRIGVG VAVLNRLLYA VGGFDGTNRL NSAECYYPER NEWRMITAMN TIRSGAGVCV LHNCIYAAGG YDGQDQLNSV ERYDVETETW TFVAPMKHRR SALGITVHQG RIYVLGGYDG HTFLDSVECY DPDTDTWSEV TRMTSGRSGV GVAVTMEPCR KQIDQQNCTC

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 325-624 of human KEAP1 (NP_036421.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-KEAP1 (ABIN3022609)

Chen, Li, Fan, Cao, Yao, Xu: "Selenium antagonizes cadmium-induced apoptosis in chicken spleen but not involving Nrf2-regulated antioxidant response." dans: Ecotoxicology and environmental safety, Vol. 145, pp. 503-510, (2017) (PubMed).

Xu, Zhang, Lu, Deng, Zhao, Zhao, Zhao: "Prevention of Hippocampal Neuronal Damage and Cognitive Function Deficits in Vascular Dementia by Dextromethorphan." dans: Molecular neurobiology, Vol. 53, Issue 5, pp. 3494-502, (2016) (PubMed).

Détails sur KEAP1

Antigène: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Autre désignation: KEAP1

Sujet: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.,KEAP1,INrf2,KLHL19,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,KEAP1

Poids moléculaire: 69 kDa

ID gène: 9817

UniProt: Q14145

Pathways: Maintenance of Protein Location