beta 2 Adrenergic Receptor anticorps (AA 334-413)

N° du produit ABIN3022784

Cet anticorps Lapin Polyclonal détecte spécifiquement beta 2 Adrenergic Receptor dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour beta 2 Adrenergic Receptor anticorps (AA 334-413) (ABIN3022784)

Antigène: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp beta 2 Adrenergic Receptor est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-beta 2 Adrenergic Receptor anticorps

Épitope: AA 334-413

Séquence: IAFQELLCLR RSSLKAYGNG YSSNGNTGEQ SGYHVEQEKE NKLLCEDLPG TEDFVGHQGT VPSDNIDSQG RNCSTNDSLL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 334-413 of human ADRB2 (NP_000015.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur beta 2 Adrenergic Receptor

Antigène: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Autre désignation: ADRB2

Sujet: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.,ADRB2,ADRB2R,ADRBR,B2AR,BAR,BETA2AR,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cardiovascular,Heart,Cardiogenesis,ADRB2

Poids moléculaire: 46 kDa

ID gène: 154

UniProt: P07550

Pathways: cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation