Cyclin B1 anticorps (C-Term)

N° du produit ABIN3022807

L’anticorps Lapin Polyclonal anti-Cyclin B1 a été validé pour WB et IF. Il convient pour détecter Cyclin B1 dans des échantillons de Humain. Il y a 5+ publications disponibles.

Aperçu rapide pour Cyclin B1 anticorps (C-Term) (ABIN3022807)

Antigène: Cyclin B1 (CCNB1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin B1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Cyclin B1 anticorps

Épitope: C-Term

Séquence: TMLDYDMVHF PPSQIAAGAF CLALKILDNG EWTPTLQHYL SYTEESLLPV MQHLAKNVVM VNQGLTKHMT VKNKYATSKH AKISTLPQLN SALVQDLAKA VAKV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 330 to the C-terminus of human Cyclin B1 (NP_114172.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Cyclin B1 (ABIN3022807)

Dong, Zheng, Wang, Tang, Yan, Zhou, Huang: "A novel HDAC6 inhibitor exerts an anti-cancer effect by triggering cell cycle arrest and apoptosis in gastric cancer." dans: European journal of pharmacology, Vol. 828, pp. 67-79, (2018) (PubMed).

Deng, Li, Zhao, Yuan, Li: "Antitumor activity of the microtubule inhibitor MBRI-001 against human hepatocellular carcinoma as monotherapy or in combination with sorafenib." dans: Cancer chemotherapy and pharmacology, Vol. 81, Issue 5, pp. 853-862, (2018) (PubMed).

Tsai, Yu, Lin, Cheng, Chen, Pang: "Prevention of Simvastatin-Induced Inhibition of Tendon Cell Proliferation and Cell Cycle Progression by Geranylgeranyl Pyrophosphate." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 149, Issue 2, pp. 326-34, (2016) (PubMed).

Cheng, Yang, Fang, Ma, Gong, Wang, Li, Xu: "Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation." dans: Nature communications, Vol. 6, pp. 7023, (2015) (PubMed).

Yu, Pang, Wu, Lin, Tseng, Tsai: "Platelet-rich plasma increases proliferation of tendon cells by modulating Stat3 and p27 to up-regulate expression of cyclins and cyclin-dependent kinases." dans: Cell proliferation, Vol. 48, Issue 4, pp. 413-20, (2015) (PubMed).

Détails sur Cyclin B1

Antigène: Cyclin B1 (CCNB1)

Autre désignation: CCNB1

Sujet: The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.,CCNB,CCNB1,Cyclin B1,cyclin B1,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cyclins,G2/M DNA Damage Checkpoint,Endocrine & Metabolism,AMPK Signaling Pathway,CCNB1

Poids moléculaire: 44 kDa/48 kDa

ID gène: 891

UniProt: P14635

Pathways: Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase