Cyclin T1 anticorps (AA 220-320)

N° du produit ABIN3022810

Cet anticorps Lapin Polyclonal détecte spécifiquement Cyclin T1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour Cyclin T1 anticorps (AA 220-320) (ABIN3022810)

Antigène: Cyclin T1 (CCNT1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin T1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cyclin T1 anticorps

Épitope: AA 220-320

Séquence: HWWEYVDATV TLELLDELTH EFLQILEKTP NRLKRIWNWR ACEAAKKTKA DDRGTDEKTS EQTILNMISQ SSSDTTIAGL MSMSTSTTSA VPSLPVSEES S

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 220-320 of human Cyclin T1 (NP_001231.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Cyclin T1

Antigène: Cyclin T1 (CCNT1)

Autre désignation: CCNT1

Sujet: This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants.,CCNT1,CCNT,CYCT1,HIVE1,cyclin-T1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Cyclins,Immunology & Inflammation,CCNT1

Poids moléculaire: 21 kDa/80 kDa

ID gène: 904

UniProt: O60563