COPS5 anticorps
Aperçu rapide pour COPS5 anticorps (ABIN302286)
Antigène
Voir toutes COPS5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody detects 38 Kda Mov34 Isologue (COPS5).
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Attributs du produit
- Synonyms: Signalosome subunit 5, SGN5, CSN5, JAB1, COP9 signalosome complex subunit 5, Junactivation domain-binding protein 1
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Purification
- Protein G chromatography
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Immunogène
- Recombinant full-length mouse JAB-1 gene expressed in E. coli
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Isotype
- IgG2a
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Indications d'application
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Immunoprecipitation. Western blot. Immunohistochemistry on paraffin sections (5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- Phosphate buffered saline
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Stock
- -20 °C
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Stockage commentaire
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Store the antibody (in aliquots) at -20 °C to -70 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
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Autre désignation
- COPS5
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Sujet
- JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the "Signalosome", which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.Synonyms: COP9 signalosome complex subunit 5, CSN5, JAB1, Jun activation domain-binding protein 1, SGN5, Signalosome subunit 5
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ID gène
- 10987
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UniProt
- Q92905
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Pathways
- Cycle Cellulaire
Antigène
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