PDE1B anticorps (AA 190-536)
Aperçu rapide pour PDE1B anticorps (AA 190-536) (ABIN3022918)
Antigène
Voir toutes PDE1B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 190-536
-
Séquence
- RHNLISRFKI PTVFLMSFLD ALETGYGKYK NPYHNQIHAA DVTQTVHCFL LRTGMVHCLS EIELLAIIFA AAIHDYEHTG TTNSFHIQTK SECAIVYNDR SVLENHHISS VFRLMQDDEM NIFINLTKDE FVELRALVIE MVLATDMSCH FQQVKTMKTA LQQLERIDKP KALSLLLHAA DISHPTKQWL VHSRWTKALM EEFFRQGDKE AELGLPFSPL CDRTSTLVAQ SQIGFIDFIV EPTFSVLTDV AEKSVQPLAD EDSKSKNQPS FQWRQPSLDV EVGDPNPDVV SFRSTWVKRI QENKQKWKER AASGITNQMS IDELSPCEEE APPSPAEDEH NQNGNLD
-
Réactivité croisée
- Humain, Souris, Rat
-
Attributs du produit
- Polyclonal Antibodies
-
Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 190-536 of human PDE1B (NP_000915.1).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid freeze / thaw cycles
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
-
Autre désignation
- PDE1B
-
Sujet
- The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,PDE1B,HEL-S-79p,PDE1B1,PDES1B,Cell Biology & Developmental Biology,Apoptosis,PDE1B
-
Poids moléculaire
- 59 kDa/61 kDa
-
ID gène
- 5153
-
UniProt
- Q01064
-
Pathways
- Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
Antigène
-