UCHL1 anticorps (AA 59-223)
Aperçu rapide pour UCHL1 anticorps (AA 59-223) (ABIN3022997)
Antigène
Voir toutes UCHL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 59-223
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Séquence
- HENFRKKQIE ELKGQEVSPK VYFMKQTIGN SCGTIGLIHA VANNQDKLGF EDGSVLKQFL SETEKMSPED RAKCFEKNEA IQAAHDAVAQ EGQCRVDDKV NFHFILFNNV DGHLYELDGR MPFPVNHGAS SEDTLLKDAA KVCREFTERE QGEVRFSAVA LCKAA
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 59-223 of human PGP9.5/PGP9.5/UCHL1 (NP_004172.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Ubiquitin C-Terminal Hydrolase L1 regulates autophagy by inhibiting autophagosome formation through its deubiquitinating enzyme activity." dans: Biochemical and biophysical research communications, Vol. 497, Issue 2, pp. 726-733, (2018) (PubMed).
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- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
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Autre désignation
- UCHL1
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Sujet
- The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.,HEL-117,HEL-S-53,NDGOA,PARK5,PGP 9.5,PGP9.5,PGP95,SPG79,Uch-L1,UCHL1,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Neuron marker,UCHL1
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Poids moléculaire
- 24 kDa
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ID gène
- 7345
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UniProt
- P09936
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Pathways
- Feeding Behaviour
Antigène
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