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Histone 3 anticorps (C-Term)

L’anticorps Lapin Polyclonal anti-Histone 3 a été validé pour WB, IHC, ChIP et IP. Il convient pour détecter Histone 3 dans des échantillons de Humain. Il y a 6+ publications disponibles.
N° du produit ABIN3023243

Aperçu rapide pour Histone 3 anticorps (C-Term) (ABIN3023243)

Antigène

Voir toutes Histone 3 (H3) Anticorps
Histone 3 (H3) (Histone H3 (H3))

Reactivité

  • 1418
  • 940
  • 842
  • 39
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Humain

Hôte

  • 1194
  • 249
  • 12
  • 5
Lapin

Clonalité

  • 1093
  • 366
  • 1
Polyclonal

Conjugué

  • 841
  • 79
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Cet anticorp Histone 3 est non-conjugé

Application

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Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP)
  • Épitope

    • 54
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    C-Term

    Séquence

    REIRRYQKST ELLIRKLPFQ RLMREIAQDF KTDLRFQSSA VMALQEACES YLVGLFEDTN LCVIHAKRVT IMPKDIQLAR RIRGERA

     Réactivité croisée

    Humain, Souris, Rat

    Attributs du produit

    Polyclonal Antibodies

    Purification

    Affinity purification

    Immunogène

    A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human HIST3H3 (NP_003484.1).

    Isotype

    IgG
  • Indications d'application

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200,ChIP,1:50 - 1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid freeze / thaw cycles

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Hou, Han, Fei, Gao, Qi, Cai, Qi: "Dietary Flavone Tectochrysin Exerts Anti-Inflammatory Action by Directly Inhibiting MEK1/2 in LPS-Primed Macrophages." dans: Molecular nutrition & food research, Vol. 62, Issue 2, (2018) (PubMed).

    Tang, Guo, Zhu, Huang, Liu, Cai, Yu, Wang: "Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation." dans: International journal of oncology, Vol. 52, Issue 6, pp. 1899-1911, (2018) (PubMed).

    Zheng, Zhou, Zhang, Thu, Xie, Lu, Pang, Xue, Xu, Chen, Chen, Li, Xu: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." dans: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).

    Su, Li, Lei, Wang, Zhao, Cai, Wang, Li, Wu: "The EZH1-SUZ12 complex positively regulates the transcription of NF-κB target genes through interaction with UXT." dans: Journal of cell science, Vol. 129, Issue 12, pp. 2343-53, (2017) (PubMed).

    Yu, Tong, Luo, Xue, Mei, Ma, Yu, Mao, Kong, Yu, Li: "Regulation of SESAME-mediated H3T11 phosphorylation by glycolytic enzymes and metabolites." dans: PLoS ONE, Vol. 12, Issue 4, pp. e0175576, (2017) (PubMed).

    Ji, Liu, Zhao, Liu, Guo, Guan, Zhou, Guo: "NF-κB Signaling is Involved in the Effects of Intranasally Engrafted Human Neural Stem Cells on Neurofunctional Improvements in Neonatal Rat Hypoxic-Ischemic Encephalopathy." dans: CNS neuroscience & therapeutics, Vol. 21, Issue 12, pp. 926-35, (2016) (PubMed).

  • Antigène

    Histone 3 (H3) (Histone H3 (H3))

    Autre désignation

    Histone H3

    Sujet

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.,H3.4,H3/g,H3FT,H3t,HIST3H3,Histone H3,HIST1H3A,Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Histone H3

    Poids moléculaire

    15 kDa

    ID gène

    8290

    UniProt

    Q16695
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