Histone 3 anticorps (C-Term)
Aperçu rapide pour Histone 3 anticorps (C-Term) (ABIN3023243)
Antigène
Voir toutes Histone 3 (H3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- REIRRYQKST ELLIRKLPFQ RLMREIAQDF KTDLRFQSSA VMALQEACES YLVGLFEDTN LCVIHAKRVT IMPKDIQLAR RIRGERA
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human HIST3H3 (NP_003484.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200,ChIP,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Dietary Flavone Tectochrysin Exerts Anti-Inflammatory Action by Directly Inhibiting MEK1/2 in LPS-Primed Macrophages." dans: Molecular nutrition & food research, Vol. 62, Issue 2, (2018) (PubMed).
: "Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation." dans: International journal of oncology, Vol. 52, Issue 6, pp. 1899-1911, (2018) (PubMed).
: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." dans: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).
: "The EZH1-SUZ12 complex positively regulates the transcription of NF-κB target genes through interaction with UXT." dans: Journal of cell science, Vol. 129, Issue 12, pp. 2343-53, (2017) (PubMed).
: "Regulation of SESAME-mediated H3T11 phosphorylation by glycolytic enzymes and metabolites." dans: PLoS ONE, Vol. 12, Issue 4, pp. e0175576, (2017) (PubMed).
: "NF-κB Signaling is Involved in the Effects of Intranasally Engrafted Human Neural Stem Cells on Neurofunctional Improvements in Neonatal Rat Hypoxic-Ischemic Encephalopathy." dans: CNS neuroscience & therapeutics, Vol. 21, Issue 12, pp. 926-35, (2016) (PubMed).
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: "Dietary Flavone Tectochrysin Exerts Anti-Inflammatory Action by Directly Inhibiting MEK1/2 in LPS-Primed Macrophages." dans: Molecular nutrition & food research, Vol. 62, Issue 2, (2018) (PubMed).
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- Histone 3 (H3) (Histone H3 (H3))
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Autre désignation
- Histone H3
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Sujet
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.,H3.4,H3/g,H3FT,H3t,HIST3H3,Histone H3,HIST1H3A,Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Histone H3
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Poids moléculaire
- 15 kDa
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ID gène
- 8290
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UniProt
- Q16695
Antigène
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