PLK1 anticorps (AA 304-603)
Aperçu rapide pour PLK1 anticorps (AA 304-603) (ABIN3023352)
Antigène
Voir toutes PLK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 304-603
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Séquence
- FFTSGYIPAR LPITCLTIPP RFSIAPSSLD PSNRKPLTVL NKGLENPLPE RPREKEEPVV RETGEVVDCH LSDMLQQLHS VNASKPSERG LVRQEEAEDP ACIPIFWVSK WVDYSDKYGL GYQLCDNSVG VLFNDSTRLI LYNDGDSLQY IERDGTESYL TVSSHPNSLM KKITLLKYFR NYMSEHLLKA GANITPREGD ELARLPYLRT WFRTRSAIIL HLSNGSVQIN FFQDHTKLIL CPLMAAVTYI DEKRDFRTYR LSLLEEYGCC KELASRLRYA RTMVDKLLSS RSASNRLKAS
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 304-603 of human PLK1 (NP_005021.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- PLK1 (Polo-Like Kinase 1 (PLK1))
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Autre désignation
- PLK1
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Sujet
- The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis, hence, it is a target for cancer therapy.,PLK1,PLK,STPK13,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,G2/M DNA Damage Checkpoint,PLK1
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Poids moléculaire
- 68 kDa
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ID gène
- 5347
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UniProt
- P53350
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Pathways
- Cycle Cellulaire, M Phase
Antigène
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