Cet anticorps anti-CD147 Monoclonal Souris (Clone CB43) (ABIN3024283) détecte spécifiquement CD147 dans FACS et IF.
L’anticorps est réactif avec des échantillons de Humain.
Optimal dilution of the Emmprin antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL
Restrictions
For Research Use only
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
4 °C,-20 °C
Stockage commentaire
Store the Emmprin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Antigène
CD147 (BSG)
(Basigin (Ok Blood Group) (BSG))
Autre désignation
Emmprin
Sujet
CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.