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CD70 anticorps

L’anticorps Souris Monoclonal anti-CD70 a été validé pour ELISA, FACS, IP, IF, IHC (fro) et InhA. Il convient pour détecter CD70 dans des échantillons de Humain.
N° du produit ABIN3024471

Aperçu rapide pour CD70 anticorps (ABIN3024471)

Antigène

Voir toutes CD70 Anticorps
CD70 (CD70 Molecule (CD70))

Reactivité

  • 108
  • 18
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 65
  • 44
  • 7
  • 2
  • 2
  • 1
Souris

Clonalité

  • 64
  • 56
  • 1
Monoclonal

Conjugué

  • 61
  • 13
  • 11
  • 9
  • 6
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CD70 est non-conjugé

Application

  • 57
  • 50
  • 50
  • 41
  • 22
  • 18
  • 18
  • 16
  • 11
  • 9
  • 8
  • 8
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Inhibition Assay (InhA)

Clone

BU69
  • Purification

    Protein G affinity chromatography

    Immunogène

    The human WM-1 (Waldenstrom s macroglobulinemia) cell line was used as the immunogen for the CD70 antibody.

    Isotype

    IgG1 kappa
  • Indications d'application

    Optimal dilution of the CD70 antibody should be determined by the researcher.

    1. This mAb blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.\. ELISA (order Ab without BSA),Functional Activity: Inhibits T cell proliferation induced by dendritic cells (Order SAF formulation) (1),Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunoprecipitation: 0.5-1 μg/500 μg protein lysate,Immunohistochemistry (Frozen): 0.5-1 μg/mL for 30 min at RT

    Restrictions

    For Research Use only
  • Concentration

    0.2 mg/mL

    Buffer

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store the CD70 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Antigène

    CD70 (CD70 Molecule (CD70))

    Autre désignation

    CD70

    Sujet

    CD70 belongs to the tumor necrosis factor (TNF) ligand family. It is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.

    Pathways

    Cancer Immune Checkpoints
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