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AMPD3 anticorps

AMPD3 Reactivité: Humain IF, ICC, FACS, IHC (p) Hôte: Souris Monoclonal AMPD3-901 unconjugated
N° du produit ABIN3025068
  • Antigène Voir toutes AMPD3 Anticorps
    AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))
    Reactivité
    • 41
    • 23
    • 20
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 29
    • 12
    Souris
    Clonalité
    • 28
    • 12
    Monoclonal
    Conjugué
    • 20
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AMPD3 est non-conjugé
    Application
    • 26
    • 13
    • 12
    • 10
    • 10
    • 8
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Attributs du produit
    It recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This mAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This mAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
    Purification
    Protein G affinity chromatography
    Immunogène
    Recombinant full-length human protein was used as the immunogen for the AMPD3 antibody.
    Clone
    AMPD3-901
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product AMPD3 Anticorps primaire
  • Indications d'application
    Optimal dilution of the AMPD3 antibody should be determined by the researcher.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Flow Cytometry: 1-2 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunocytochemistry: 1-2 μg/mL for 30 min at RT,Immunohistology (FFPE): 2-4 μg/mL for 30 min at RT (1),Prediluted format : incubate for 30 min at RT (2)

    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store the AMPD3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Antigène
    AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))
    Autre désignation
    AMPD3 (AMPD3 Produits)
    Synonymes
    anticorps ampd3, anticorps fi25h10, anticorps wu:fi25h10, anticorps zgc:55390, anticorps MGC108215, anticorps adenosine monophosphate deaminase 3, anticorps adenosine monophosphate deaminase 3b, anticorps AMP deaminase 3, anticorps AMPD3, anticorps ampd3b, anticorps PTRG_08116, anticorps ampd3, anticorps Ampd3
    Sujet
    It recognizes a protein of ~90  kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This mAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This mAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
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