BAI1 anticorps (N-Term)

N° du produit ABIN302508

Détail du produit anti-BAI1 anticorps

Antigène: BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAI1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects Brain-Specific Angiogenesis Inhibitor 1 (BAI1) at N-terminal domain.

Purification: Immunoaffinity chromatography

Immunogène: BAI1 antibody was raised against synthetic peptide from N-terminal domain of human BAI1.

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections (20 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.7 mg/mL

Buffer: PBS containing 0.09 % sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Détails sur BAI1

Antigène: BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Autre désignation: BAI1 (BAI1 Produits)

Synonymes: anticorps BAI1, anticorps GDAIF, anticorps B830018M07Rik, anticorps R75078, anticorps mKIAA4089, anticorps brain-specific angiogenesis inhibitor 1, anticorps adhesion G protein-coupled receptor B1, anticorps BAI1, anticorps ADGRB1, anticorps LOC100228084, anticorps Adgrb1

Sujet: BAI1 is an Orphan-B GPCR with an unknown ligand. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis, and a growth suppressor of glioblastoma. Along with BAI1, there are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3, which have similar tissue specificities and structures. However, only BAI1 is transcriptionally regulated by p53. Loss of BAI1 expression has been implicated in glioblastoma.Synonyms: BAI-1, Brain-specific angiogenesis inhibitor 1

ID gène: 575

NCBI Accession: NP_001693

UniProt: O14514

Pathways: Signalisation p53