ADRA1B anticorps (Cytoplasmic Domain)
Aperçu rapide pour ADRA1B anticorps (Cytoplasmic Domain) (ABIN302517)
Antigène
Voir toutes ADRA1B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Cytoplasmic Domain
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Specificité
- This antibody detects Alpha 1b-Adrenoceptor (ADRA1B) at 3rd cytoplasmic domain.
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Purification
- Immunoaffinity chromatography
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Immunogène
- ADRA1B antibody was raised against synthetic peptide from 3rd cytoplasmic domain of human ADRA1B.
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Indications d'application
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Immunohistochemistry on paraffin sections (10 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.09 % sodium azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))
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Autre désignation
- alpha-1B Adrenergic Receptor
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Sujet
- The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation.Synonyms: ADRA1B, Alpha 1B-adrenoceptor, Alpha 1B-adrenoreceptor
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ID gène
- 147
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NCBI Accession
- NP_000670
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UniProt
- P35368
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Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Antigène
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