PDE8A anticorps (N-Term)

N° du produit ABIN302523

Détail du produit anti-PDE8A anticorps

Antigène: PDE8A (phosphodiesterase 8A (PDE8A))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE8A est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects Phosphodiesterase 8A (PDE8A) near N-terminus.

Purification: Immunoaffinity chromatography

Immunogène: PDE8A antibody was raised against synthetic peptide from near N-terminus of human PDE8A.

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections (10 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Détails sur PDE8A

Antigène: PDE8A (phosphodiesterase 8A (PDE8A))

Autre désignation: PDE8A (PDE8A Produits)

Synonymes: anticorps PDE8A, anticorps Pde8a, anticorps HsT19550, anticorps AI551852, anticorps Pde8, anticorps RNPDE8A, anticorps phosphodiesterase 8A, anticorps PDE8A, anticorps Pde8a, anticorps pde8a

Sujet: Phosphodiesterase 8A, a high affinity, cAMP-specific phosphodiesterase, has been implicated in penile erectile dysfunction. PDE8A activity is inhibited by dipyridamole, but not by rolipram, zaprinast, or IBMX. At least five splice variants and four protein isoforms have been reported.Synonyms: 5'-cyclic phosphodiesterase 8A, FLJ16150, High affinity cAMP-specific and IBMX-insensitive 3', HsT19550, Phosphodiesterase 8A, cAMP-specific cyclic nucleotide phosphodiesterase 8A

ID gène: 5151

NCBI Accession: NP_002596

UniProt: O60658

Pathways: cAMP Metabolic Process