PDE6A anticorps (N-Term)

N° du produit ABIN302532

Cet anticorps anti-PDE6A Polyclonal Lapin (ABIN302532) détecte spécifiquement PDE6A dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PDE6A anticorps (N-Term) (ABIN302532)

Antigène: PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE6A est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PDE6A anticorps

Épitope: N-Term

Specificité: This antibody detects Phosphodiesterase 6A (PDE6A) at N-terminal region.

Purification: Immunoaffinity chromatography

Immunogène: PDE6A antibody was raised against synthetic peptide from N-terminal region of human PDE6A / PDE6 Alpha.

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.23 mg/mL

Buffer: PBS containing 0.09 % sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Détails sur PDE6A

Antigène: PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))

Autre désignation: PDE6A

Sujet: Phosphodiesterase 6A, a catalytic subunit of the photoreceptor phosphodiesterase, has been shown to affect functioning of eye retina as the alpha subunit of the heterotetrameric rod photoreceptor. Mutations in PDE6A have been identified as a cause of autosomal recessive retinitis pigmentosa.Synonyms: 5'-cyclic phosphodiesterase subunit alpha, GMP-PDE alpha, PDE V-B1, PDE6 alpha, PDEA, Phosphodiesterase 6A, Phosphodiesterase-6A cGMP-specific, Rod cGMP-specific 3'

ID gène: 5145

NCBI Accession: NP_000431

UniProt: P16499

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction