PLAP anticorps (full length)

N° du produit ABIN3025399

Cet anticorps anti-PLAP Monoclonal Souris (Clone ALPP-516) (ABIN3025399) détecte spécifiquement PLAP dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PLAP anticorps (full length) (ABIN3025399)

Antigène: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PLAP est non-conjugé

Application: ELISA

Clone: ALPP-516

Détail du produit anti-PLAP anticorps

Épitope: full length

Fonction: Placental Alkaline Phosphatase Antibody

Purification: Protein G affinity chromatography

Immunogène: Recombinant full-length human ALPP protein was used as the immunogen for the Placental Alkaline Phosphatase antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Placental Alkaline Phosphatase antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Placental Alkaline Phosphatase antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur PLAP

Antigène: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Autre désignation: Placental Alkaline Phosphatase

Sujet: PLAP is a tissue specific, trophoblast-derived, 70 kDa, glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2+ metallo-glycoprotein that catalyzes the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. It is present in the placenta and serum of pregnant women and in high frequency in gynecological and testicular cancers and in lower frequency in other tumors. The three tissue-specific AP's in humans, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98 % homologous. Non-tissue specific AP is found in kidney, liver and bone. This mAb binds equally well to all common allelic variants (S, F, FS and I) of PLAP and to some variants of AP from normal human testis. This mAb can be used as tracer antibody in ELISA to detect PLAP in serum of S, F, FS and I phenotypes.

UniProt: P05187