HTR7 anticorps (C-Term)
Aperçu rapide pour HTR7 anticorps (C-Term) (ABIN302548)
Antigène
Voir toutes HTR7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- This antibody detects 5-HT7 Receptor (HTR7) at C-terminal region.
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Réactivité croisée (Details)
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Species reactivity (expected):Gorilla, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig (100 % immunogen sequence identity).
Species reactivity (tested):Human. -
Purification
- Immunoaffinity Chromatography
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Immunogène
- HTR7 antibody was raised against synthetic peptide from C-terminal region of human HTR7 / 5-HT7.
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Indications d'application
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Immunohistochemistry on Paraffin Sections (10 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))
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Autre désignation
- Serotonin Receptor 7 (HTR7)
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Sujet
- 5-HT7 Receptor is a Serotonin Receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract. This receptor has been implicated in depression, autistism, and other neuropsychiatric disorders. Three protein isoforms have been documented: isoform a: 445aa, isoform b: 432aa, isoform d: 479aa.Synonyms: 5-HT-7, 5-hydroxytryptamine receptor 7, 5HT7
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ID gène
- 3363
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NCBI Accession
- NP_000863
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UniProt
- P34969
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Pathways
- Signalistation JAK/STAT
Antigène
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