S100A8/A9 Complex (Calprotectin) anticorps

N° du produit ABIN3025523

Cet anticorps Souris Monoclonal détecte spécifiquement S100A8/A9 Complex (Calprotectin) dans FACS, IF et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour S100A8/A9 Complex (Calprotectin) anticorps (ABIN3025523)

Antigène: S100A8/A9 Complex (Calprotectin) (S100A8/A9) (Calprotectin (S100A8/A9))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp S100A8/A9 Complex (Calprotectin) est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CAGB-426

Détail du produit anti-S100A8/A9 Complex (Calprotectin) anticorps

Purification: PEG precipitation

Immunogène: Recombinant human protein was used as the immunogen for the Calgranulin A + B antibody.

Isotype: IgM kappa

Information d'application

Indications d'application: Optimal dilution of the Calgranulin A + B antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (Formalin-fixed): 0.5-1 μg/mL for 30 min at RT (1),Not suitable for frozen tissues

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Calgranulin A + B antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur S100A8/A9 Complex (Calprotectin)

Antigène: S100A8/A9 Complex (Calprotectin) (S100A8/A9) (Calprotectin (S100A8/A9))

Autre désignation: Calgranulin A + B

Sujet: Recognizes a 12-14  kDa doublet of Calgranulin A/B (also known as S100A8/A9 or MRP-8/14), expressed by granulocytes, monocytes and by tissue macrophages. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of this protein is associated with the disease cystic fibrosis. This mAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.

Pathways: S100 Proteins