VCAM1 anticorps

N° du produit ABIN3025722

L’anticorps anti-VCAM1 Monoclonal Souris est utilisé pour la détection de VCAM1 dans des échantillons de Humain. Il a été validé pour FACS et IF.

Aperçu rapide pour VCAM1 anticorps (ABIN3025722)

Antigène: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VCAM1 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: B-K9

Détail du produit anti-VCAM1 anticorps

Fonction: VCAM1 Antibody

Séquence: HUVEC

Purification: Protein G affinity chromatography

Immunogène: Activated human umbilical vein endothelial cells (HUVEC) were used as the immunogen for the VCAM1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the VCAM1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the VCAM1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur VCAM1

Antigène: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Autre désignation: VCAM1

Sujet: Recognizes a protein of 110 kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1), L1CAM and INCAM-100). It is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. L1CAM serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This mAb inhibits the binding of leukocytes to L1CAM on stimulated endothelial cells.

UniProt: P19320

Pathways: Carbohydrate Homeostasis