IFNA2 anticorps

N° du produit ABIN3025780

Cet anticorps anti-IFNA2 est un anticorps Souris Monoclonal détectant IFNA2 dans ELISA. Adapté pour Humain.

Aperçu rapide pour IFNA2 anticorps (ABIN3025780)

Antigène: IFNA2 (Interferon, alpha 2 (IFNA2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNA2 est non-conjugé

Application: ELISA

Clone: N39

Détail du produit anti-IFNA2 anticorps

Purification: Protein G affinity chromatography

Immunogène: Purified recombinant human IFNA2 was used as the immunogen for the Interferon alpha 2 antibody.

Isotype: IgG kappa

Information d'application

Indications d'application: Optimal dilution of the Interferon alpha 2 antibody should be determined by the researcher.\. ELISA: order BSA/azide-free format for coating

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Interferon alpha 2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur IFNA2

Antigène: IFNA2 (Interferon, alpha 2 (IFNA2))

Autre désignation: Interferon alpha 2

Sujet: Recognizes a protein of 16-27  kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This mAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this mAb is called "site I" and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 mAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C