BACE1 anticorps (Internal Region)

N° du produit ABIN302584

Cet anticorps Lapin Polyclonal détecte spécifiquement BACE1 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour BACE1 anticorps (Internal Region) (ABIN302584)

Antigène: BACE1 (Beta-secretase 1 (BACE1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BACE1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BACE1 anticorps

Épitope: Internal Region

Specificité: This antibody deztects Beta-site APP-Cleaving Enzyme 1 (BACE1) at internal domain.

Purification: Immunoaffinity chromatography

Immunogène: BACE1 antibody was raised against synthetic peptide from internal domain of human BACE1.

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections (2.5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 °C to 8 °C up to one month or (in aliquots) at -20 °C to -70 °C for longer.

Détails sur BACE1

Antigène: BACE1 (Beta-secretase 1 (BACE1))

Autre désignation: BACE1

Sujet: Bace 1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.Synonyms: ASP2, Aspartyl protease 2, BACE, BACE-1, Beta-secretase 1, Beta-site APP cleaving enzyme 1, Beta-site amyloid precursor protein cleaving enzyme 1, KIAA1149, Memapsin-2, Membrane-associated aspartic protease 2

ID gène: 23621

NCBI Accession: NP_036236

UniProt: P56817