CD55 anticorps

N° du produit ABIN3026018

Cet anticorps Souris Monoclonal détecte spécifiquement CD55 dans FACS, IF et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour CD55 anticorps (ABIN3026018)

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD55 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 143-30

Détail du produit anti-CD55 anticorps

Purification: Protein G affinity chromatography

Immunogène: PHA stimulated human PBL were used as the immunogen for the CD55 antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal dilution of the CD55 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (Frozen): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CD55 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur CD55

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Autre désignation: CD55 (DAF)

Sujet: Recognizes a single chain glycoprotein of 70  kDa, identified as CD55 (also known as decay accelerating factor, DAF). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The mAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity